Apple Extract Phloretin 95%

Apple Extract Phloretin 95% | Pharmaceutical-Grade Cosmetic Active

≥95% pure (HPLC verified) | NSF GMP and FSSC22000 certified | In-stock and ready to ship

Earth Made Nutritions sells Apple Extract Phloretin 95%, a high-purity phloretin extract (CAS: 60-82-2) for cosmetic manufacturers across North America. Our ethanol-extracted powder contains 95%+ active ingredients and is suitable for use in antioxidant serums, brightening products, and advanced skin care formulations.

Key Supply Benefits:

• Minimum 25kg order | Same-day processing
• 4 US warehouses with 48-hour delivery to key metros
• Receive a free 50g sample with technical data.
• Includes batch-specific COA, MSDS, and formulation support.

 Recommended Use Levels

• 0.5% to 2.0% antioxidant serums
• treatments that lighten the skin: 1.0 to 3.0%
• 1.0 to 2.0% of acne and oil control products
• 0.5-1.5% of anti-aging creams

How Aqueous Formulations Are Typically Dissolved:

1. Mix phloretin and ethanol in a 1:10 weight ratio.

2. Add ethanol solution when the temperature is below 40°C during the cool-down period.

3. To get an equal distribution, mix everything well for 5 to 10 minutes.

Key Properties and Specifications

Applications in Cosmetic Formulations

1. Advanced Antioxidants
Phloretin alters dermal cell lipid bilayer potential, allowing co-applied antioxidants such L-ascorbic acid and ferulic acid to penetrate. Its mechanism is useful in:

• C+E+Ferulic serum formulations
• Day creams for environmental protection
• Recovery items after operation

The chemical provides multi-level antioxidant protection by neutralizing peroxynitrite radicals and inhibiting lipid peroxidation.

2. Brightening, Hyperpigmentation

Phloretin suppresses MITF expression to regulate upstream melanogenesis, unlike tyrosinase inhibitors. The outcome is:

Gradual, uniform tone improvement without hyperpigmentation rebound.

• Suitable for sensitive skin types
• Compatible with niacinamide and alpha-arbutin.
• Uses: spot treatments, brightening serums, daily tone-correcting moisturizers.

3. Manage Sebum and Acne

Phloretin inhibits Cutibacterium acnes and decreases sebum oxidation, particularly squalene peroxidation. Formulators add it to:

• Lotions for oily skin that mattify
• Non-comedogenic acne remedies
• Toners for pore refinement

Effective in leave-on cosmetics at 1-2%. Compatible with salicylic acid and zinc derivatives.

Quality Control & Testing

Five steps are used to check the quality of each production batch:

1. Tests of Identity and Purity

HPLC analysis confirms that Apple Extract Phloretin 95% has a phloretin content of at least 95% and a normal retention time, distinguishing it from lower-quality extracts that contain phloridzin or other dihydrochalcone impurities.

2. Analysis of Residual Solvent

The GC test makes sure that the levels of ethanol and methanol residues are below the limits set by USP <467> (<5,000 ppm), which meets safety standards for facial application.

3. Screening for Heavy Metal

Lead, arsenic, cadmium, and mercury levels were checked using ICP-MS in line with FDA and EU cosmetic rules.

4. Testing for Microbe Safety

As per ISO 17516, the total plate count, the yeast/mold count, and the disease screens (E. coli, Salmonella, S. aureus, and P. aeruginosa) must all be done.

5. An Analysis of Pesticide Residues

Screening for more than 450 chemicals using multiple residues in line with EU Regulation 1223/2009 Annex II and III.

Giving Documentation:

• Certificate of Analysis for a specific batch
• Safety Data Sheet for Materials (MSDS/SDS)
• Allergen notice
• GMO-free declaration
• BSE/TSE-free certificate

Supply & Logistics

Currently in stock at 4 US distribution sites (CA, TX, NJ, IL).

Processing orders:

• Orders ordered by 2 PM PST ship same day.
• 2nd-day delivery available in major urban regions.
• International shipment via DHL/FedEx (3-5 business days)

Minimum Order: 25kg (1 drum).

Free 50g sample for qualified formulators (one-time, shipping included)

Ask for current bulk pricing and volume discounts.

FAQ

Q: How is 95% phloretin different from apple extracts?

A: Standard apple polyphenol extracts include 20-40% mixed phenolics (chlorogenic acid, epicatechin, phloridzin). Our product isolates phloretin with ≥95% purity, ensuring consistent activity and predictable formulation.

Q: How stable is phloretin in finished formulations?

A: Protected from light, phenol is stable around pH 3.5-6.5. I recommend opaque or amber packaging. Stability is improved by tocopherol and ferulic acid. Avoid forming beyond 60°C.

Q: Can "natural" or "organic" cosmetics utilize this?

A: Yes. Most natural cosmetic standards (COSMOS, NATRUE) allow ethanol extraction. USDA-certified organic formulation batches are available. Verify certifier requirements.

Q: Is phloretin suitable for sensitive skin products?

A: Clinical studies indicate good tolerance at ≤2% concentration. Non-irritating and non-sensitizing in HRIPT. Suitable for sensitive skin formulations when patch-tested in final product.

Q: What distinguishes phloretin from phloridzin?

A: Glycosylated phloridzin is phloretin + glucose. We use free phloretin for better skin penetration and absorption. Phloridzin impurities are common in low-quality extracts.

Q: Do you offer smaller quantities for R&D?

A: Qualified formulators receive 50g samples for free. Custom packaging is available for R&D (1-5kg). Contact our technical team.

Request Sample or Place Order

Ready to test phloretin in your formulations with Apple Extract Phloretin 95%?

Email info@em-herb.com