Name: Polygonum Cuspidatum Extract 98% resveratrol
SKU: N/A

Polygonum Cuspidatum Extract 98% Trans-Resveratrol

Since 2018, Earth Made Nutritions Inc. has sold confirmed botanical products to companies that make supplements and cosmetics. Our Polygonum Cuspidatum Extract 98% resveratrol has 98% Trans-Resveratrol, which has been proven by HPLC testing and is backed by a lot of quality documentation.

Quick Specifications:

· Purity:≥98.0% Trans-Resveratrol (HPLC verified)

· Emodin Control:<1% (Premium grade: <0.2%)

· Origin Verified:Carbon-14 tested for natural sourcing

· Availability:In-stock at 4 U.S. warehouses

· Certifications:NSF GMP, FSSC22000, Kosher, Halal, Organic available

Polygonum Cuspidatum Extract 98% resveratrol

Product Overview

What Is This Ingredient?

Polygonum Cuspidatum Extract is concentrated from Giant Knotweed rhizomes using pharmaceutical-grade ethanol extraction. The 98% specification refers to Trans-Resveratrol content—the active isomer required for biological activity.

Product Specifications

Parameter	Specification
Latin Name	Polygonum Cuspidatum
Specification	98% Resveratrol
Solvent Used	Ethanol
Appearance	Fine White Powder
Plant Part Used	Rhizome
Package	25kgs/drum
MOQ	25kgs
Sample	Free Sample Available
Lead Time	In stock, 2nd day picking up
Certificates	NSF GMP, FSSC22000, Kosher, Halal, ISO, Organic

Applications & Formulation Guidance

Dietary Supplements

Lifelong & Cellular Health Options

Typical serving: 250-500mg

Pairs well with NMN, NAD+ precursors, and pterostilbene.

For water-based forms, lipid carrier or complexation is needed.

Cardiovascular & Metabolic Support

· Dosage range: 150-500mg daily

· Compatible with: CoQ10, omega-3, berberine

· Stability consideration: Use light-protective packaging

Cosmetic & Skincare

Antioxidants & Anti-Aging

The topical product concentration is 0.5-2%.

Liposomal encapsulation and cyclodextrin complexation are delivery techniques.

Needs oil or solubilizer for solubility.

Stability: Apply antioxidant stabilisers to prevent oxidation.

Skin Brightening Products

· Mechanism: Tyrosinase inhibition

· Formulation: Combine with stable emulsion systems

· Packaging: Airless or opaque containers recommended

Functional Foods & Beverages

Challenges with water-based products:

· Low water solubility

· Photosensitivity (degrades under UV)

Solutions:

· Prepare as cold-water-soluble (CWS) format

· Use solid dispersion technology

· Encapsulate with spray-dried carriers

· Consider cyclodextrin complexation

We provide formulation support for beverage applications—contact us for technical consultation.

Applications and Uses

Quality Testing & Verification

We test every batch of Polygonum Cuspidatum Extract 98% resveratrol against pharmaceutical-grade standards. Documentation is provided with all shipments.

Standard Testing Protocol

Identity & Purity

· HPLC analysis for Trans-Resveratrol content

· Isomer ratio verification (Trans vs. Cis)

· Melting point: 253-255°C

Contaminant Screening

· Heavy metals: ICP-MS testing

· Pesticides: Multi-residue GC/LC-MS screen

· PAH4: <10ppb, Benzo(a)pyrene <2ppb

· Emodin quantification: HPLC

Natural Origin Confirmation

· Carbon-14 testing available (verifies plant-derived source)

· Distinguishes natural extract from synthetic resveratrol

Microbial & Solvent Residues

· Total plate count, yeast/mold, pathogens

· Ethanol and ethyl acetate: USP <467> limits

Each Certificate of Analysis (COA) includes test results, batch numbers, and manufacturing dates.

R&D and Quality

Why Work With Earth Made Nutritions?

Manufacturing & Distribution Infrastructure

Domestic Supply Chain

· California-based processing facility

· 4 warehouses across the United States

· In-stock inventory for immediate fulfillment

· 2nd-day pickup available for urgent orders

Quality System Certifications

· NSF GMP Registered

· FSSC22000 (Food Safety)

· Kosher & Halal certified

· ISO 9001:2015

· Organic handling certified (for organic products)

Service & Support

Technical Assistance

Our team includes formulators experienced with botanical extracts. We provide:

· Solubility and stability guidance

· Suggested delivery systems

· Regulatory documentation support

· Custom specifications (micronization, organic, etc.)

Complete Documentation

Every shipment includes:

· Certificate of Analysis (COA)

· Allergen statement

· GMO-free declaration

· BSE/TSE statement

· Kosher/Halal certificates (when applicable)

· MSDS/SDS

· Customs/phytosanitary certificates (for exports)

Sampling Program

Request free samples to test compatibility with your formulations. Samples typically ship within 48 hours.

Certification

Storehouse

Properties & Handling Information

Physical Characteristics

· Appearance:Fine white powder (any yellowing indicates oxidation)

· Particle size:95% pass 80 mesh (custom micronization available)

· Melting point:253-255°C

· Bulk density:0.4-0.6 g/mL

Solubility Profile

Solvent	Solubility
Water	Poorly soluble (<0.05 mg/mL)
Ethanol	Freely soluble
DMSO	Soluble
Alkaline solution	Soluble (pH >9)
Oil phase	Requires solubilizer

Formulation tip:For aqueous systems, use cyclodextrin complexation or prepare as nanoparticles/liposomes.

Stability Considerations

Light sensitivity:UV exposure converts Trans-Resveratrol to less-active Cis form

· Store in amber containers

· Process under low-light conditions

· Use opaque packaging for finished products

Oxidation:Resveratrol is prone to oxidative degradation

· Add antioxidant stabilizers (vitamin E, ascorbic acid)

· Minimize air exposure during processing

· Use nitrogen flushing for long-term storage

Temperature:Store below 25°C in sealed containers

Humidity:Keep relative humidity <60%

FAQ

Q: Is this extract naturally derived or synthetic?

A: Naturally extracted from Polygonum cuspidatum rhizomes. We conduct Carbon-14 testing to verify plant origin. This test measures isotopic carbon signatures—plant-based compounds show modern atmospheric ratios, while synthetic versions (from petrochemicals) show depleted ratios.

Test reports are available on request.

Q: What is the difference between 98% and lower-purity extracts?

A: Higher purity means:

· More active ingredient per gram (better dose efficiency)

· Smaller capsule sizes possible

· Lower Emodin content (reduces laxative effects)

· Better cost-per-dose at finished product level

A 250mg capsule of 98% extract delivers 245mg Trans-Resveratrol. With a 50% extract, you'd need 500mg to match it.

Q: How is Emodin controlled?

A: Emodin is a natural compound in Polygonum cuspidatum with potential laxative effects. We offer two grades:

· Standard:<1% Emodin (suitable for most applications)

· Premium:<0.2% Emodin (for sensitive formulations)

Specify your preference when ordering.

Q: Can this be used in organic-certified products?

A: Yes, when sourced through our organic supply chain. Our facility maintains organic handling certification. We provide the documentation required by certifying bodies (USDA, EU, etc.).

Indicate "organic required" when requesting a quote.

Q: What testing do you perform on each batch?

A: Every batch undergoes:

· HPLC for Trans-Resveratrol content and Emodin

· Heavy metal screening (ICP-MS)

· Pesticide multi-residue analysis

· Microbial testing (TPC, yeast/mold, pathogens)

· Solvent residue testing (GC)

We also conduct periodic PAH testing and can arrange Carbon-14 testing for customers requiring natural origin verification.

Q: What is the typical shelf life?

A: 24 months when stored properly:

· Sealed containers

· Temperature below 25°C

· Low humidity (<60% RH)

· Protected from light

For finished products, shelf life depends on formulation and packaging. We recommend stability testing under your specific conditions.

Q: Do you offer samples?

A: Yes. Free samples are available to qualified manufacturers and formulators. This allows you to:

· Verify quality and purity

· Test compatibility with your formulation

· Conduct analytical method validation

· Perform stability studies

Samples typically ship within 48 hours. Request via email below.

Q: What is the minimum order quantity?

A: Standard MOQ is 25kg (one drum). For larger volume requirements or custom specifications, contact us to discuss options.

Q: Can you provide references or case studies?

A: We work with confidential manufacturing relationships, but can provide references from non-competing industries upon request. Contact us to discuss your specific application.

Storage & Handling Recommendations

Receiving inspection:

· Verify packaging integrity

· Check COA against sample appearance

· Confirm batch number matches documentation

· Conduct melting point test (253-255°C) for identity

Storage conditions:

· Temperature: 15-25°C

· Humidity: <60% RH

· Light: Store in opaque or amber containers

· Atmosphere: Nitrogen flushing recommended for long-term storage

Handling precautions:

· Use in well-ventilated areas

· Avoid dust generation

· Wear gloves and safety glasses

· Refer to MSDS for complete safety information

Repackaging:

· Use moisture-proof containers

· Flush with nitrogen before sealing

· Label with batch number and repackaging date

· Store away from incompatible materials

Regulatory & Compliance Information

United States:

· Generally Recognized as Safe (GRAS) for use in dietary supplements

· Complies with FDA CFR Title 21

· Meets USP standards for botanical extracts

European Union:

· Complies with EU Novel Food Regulations (where applicable)

· PAH and pesticide limits meet EU standards

· Available with EU-compliant documentation

Other Markets:

· Health Canada NPN-ready documentation available

· TGA (Australia) compliant specifications

· Halal and Kosher certified batches available

We provide regulatory support documentation for product registration in various jurisdictions. Specify your target market when requesting information.