active pqq

Active PQQ (Pyrroloquinoline Quinone): Pharmaceutical-Grade Mitochondrial Support Ingredient

Earth Made Nutritions Inc.| California-Based Supplier | NSF GMP Certified

Product Specifications

Product Overview

Specification:Pyrroloquinoline Sodium quinone

Purity: ≥98% (HPLC verification)

Nonsynthetic bacterial fermentation Source

122628-50-6 CAS.

Powder:Fine reddish-brown

Medical supplement and functional food producers use our pharmaceutical-grade Active PQQ. To ensure purity, heavy metal limitations, and microbiological safety, each batch is third-party tested.

Quality Certifications

Our manufacturing facilities hold current certifications for:

· NSF GMP(Dietary Supplements)

· FSSC 22000(Food Safety Management)

· ISO 9001:2015(Quality Management)

· Kosher(Orthodox Union certified)

· Halal(Islamic Food and Nutrition Council of America)

· USDA Organic(for fermentation substrates)

Certificates available upon request for qualified customers.

Applications in Formulation Development

Cognitive Health Supplements

Neuronal mitochondria activity is supported by active PQQ. Neuroprotective characteristics have been shown with CoQ10.

Average Dosage:10-20 mg/serving

Compatible: Hard capsules, pills, powders

Stability: Suitable for common supplement matrices but needs mild protection.

Energy & Metabolic Support Products

The disodium salt form offers superior water solubility for beverage applications.

Beverage Compatibility:

· pH stability range: 3.0-7.0

· Heat stable through pasteurization (72°C, 15 seconds)

· Requires opaque or UV-blocking packaging

Formulation Tip:Avoid strongly alkaline environments (pH >7.0) to maintain stability.

Longevity & Healthy Aging Formulas

PQQ's redox cycling mechanism provides antioxidant capacity distinct from Vitamin C or E. It performs catalytic cycles rather than one-time electron donation.

Synergistic Combinations:

· Ubiquinol (reduced CoQ10)

· Alpha-lipoic acid

· Resveratrol

Supply Chain Advantages

U.S.-Based Inventory Network

We maintain inventory at four strategic warehouse locations:

· West Coast:California

· Southwest:Texas

· Midwest:Illinois

· East Coast:New Jersey

Standard Lead Time:2-3 business days for in-stock orders

Minimum Order Quantity:25 kg (1 drum)

Quality Documentation Provided

Each shipment includes:

· Certificate of Analysis (CoA)

· Material Safety Data Sheet (MSDS/SDS)

· Allergen Statement

· BSE/TSE Statement

· GMO-Free Declaration

· Country of Origin Certificate

Regulatory Status

· U.S. FDA:GRAS status (Generally Recognized as Safe)

· EU:Novel Food approval (Commission Regulation 2015/2283)

· Canada:Natural Health Product eligible ingredient

· Australia/New Zealand:Listed substance (FSANZ)

Regulatory status verification recommended for specific target markets.

Formulation Support & Technical Resources

Our R&D team provides:

· Stability testing guidance

· Excipient compatibility recommendations

· Dosage form development consultation

· Regulatory documentation support

Note:We do not provide medical claims or finished product marketing language. Customers are responsible for ensuring their product claims comply with applicable regulations.

FAQ

Q: What is the difference between PQQ disodium salt and PQQ acid?

A: High water solubility (~60 mg/mL vs. <1 mg/mL) and improved gastrointestinal absorption are advantages of disodium salt. Reduced dosage improves bioavailability.

Q: Is this ingredient vegan/vegetarian?

A: Yes. Using bacterial fermentation, we make our product without animal products.

Q: What causes the powder to clump during storage?

A: PQQ disodium salt readily absorbs air moisture. Reseal containers immediately and keep in low-humidity conditions (<60% RH).

Q: Can gummies use it?

A: PQQ's moderate taste and light sensitivity make gummy matrices difficult. To maximize stability, take hard capsules or tablets.

Q: What documentation do you provide for export orders?

A: You may get commercial invoices, packing lists, certificates of origin, and phytosanitary certifications from us.

Q: Can you private label or manufacture products?

A: We offer raw ingredients. For contract manufacturing references, contact us.

Request Information

For technical data sheets, samples, or pricing inquiries for active pqq, contact our customer support team:

Email:info@em-herb.com